2024

• Elucidating lactate metabolism in industrial CHO cultures through the combined use of flux balance and principal component analyses M Luginsland, C Kontoravdi, A Racher, C Jaques, A Kiparissides; Biochemical Engineering journal 202, 109184
• Machine Learning Integrating Protein Structure, Sequence, and Dynamics to Predict the Enzyme Activity of Bovine Enterokinase Variants NA Venanzi, A Basciu, AV Vargiu, A Kiparissides, PA Dalby and D Dikicioglu; J. Chem. Inf. Model., 10.1021/acs.jcim.3c00999
• Advanced Modeling of Biomanufacturing Processes G Penloglou, A Kiparissides; Processes 2024, 12(2), 387

2022

• Shedding light on phototrophic biomass production of Chlorella variabilis: The importance of dissolved CO2, light intensity and duty cycle M Booth, A Spicer, A Kiparissides; Biochemical Engineering journal 179, 108315

2021

• The effects of illumination and trophic strategy on gene expression in Chlamydomonas reinhardtii V Sanchez-Tarre, A Kiparissides; Algal Research 54, 102186

2009 – 2020

• Improving the accuracy of flux balance analysis through the implementation of carbon availability constraints for intracellular reactions M Lularevic, AJ Racher, C Jaques, A Kiparissides; Biotechnology and Bioengineering 116 (9), 2339-2352
• Thermodynamics-based Metabolite Sensitivity Analysis in metabolic networks A Kiparissides, V Hatzimanikatis; Metabolic Engineering 39, 117-127
• On the model‐based optimization of secreting mammalian cell (GS‐NS0) cultures A Kiparissides, EN Pistikopoulos, A Mantalaris; Biotechnology and Bioengineering 112 (3), 536-548
• Design of in silico experiments as a tool for nonlinear sensitivity analysis of knowledge-driven models A Kiparissides, C Georgakis, A Mantalaris, EN Pistikopoulos; Industrial & Engineering Chemistry Research 53 (18), 7517-7525
• Improving embryonic stem cell expansion through the combination of perfusion and bioprocess model design D Yeo, A Kiparissides, JM Cha, C Aguilar-Gallardo, JM Polak, E Tsiridis, … et al.; PLoS One 8 (12), e81728
• An in silico erythropoiesis model rationalizing synergism between stem cell factor and erythropoietin THH Phan, P Saraf, A Kiparissides, A Mantalaris, H Song, M Lim; Bioprocess and Biosystems Engineering 36, 1689-1702
• Bioprocess systems engineering: transferring traditional process engineering principles to industrial biotechnology M Koutinas, A Kiparissides, EN Pistikopoulos, A Mantalaris; Computational and Structural Biotechnology journal 3 (4), e201210022
• Computational approach for understanding and improving GS-NS0 antibody production under hyperosmotic conditions Y Ho, A Kiparissides, EN Pistikopoulos, A Mantalaris; Journal of Bioscience and Bioengineering 113 (1), 88-98
• Improving the prediction of Pseudomonas putida mt-2 growth kinetics with the use of a gene expression regulation model of the TOL plasmid M Koutinas, A Kiparissides, MC Lam, R Silva-Rocha, M Godinho, … et al.; Biochemical Engineering journal 55 (2), 108-118
• Linking genes to microbial growth kinetics—An integrated biochemical systems engineering approach M Koutinas, A Kiparissides, R Silva-Rocha, MC Lam, VAPM Dos Santos, … et al.; Metabolic Engineering 13 (4), 401-413
• ‘Closing the loop’in biological systems modeling—From the in silico to the in vitro A Kiparissides, M Koutinas, C Kontoravdi, A Mantalaris, EN Pistikopoulos; Automatica 47 (6), 1147-1155
• Modelling the Delta1/Notch1 pathway: in search of the mediator (s) of neural stem cell differentiation A Kiparissides, M Koutinas, T Moss, J Newman, EN Pistikopoulos, … et al.; PLoS One 6 (2), e14668
• The regulatory logic of m‐xylene biodegradation by Pseudomonas putida mt‐2 exposed by dynamic modelling of the principal node Ps/Pr of the TOL plasmid M Koutinas, MC Lam, A Kiparissides, R Silva‐Rocha, M Godinho, … et al.; Environmental Microbiology 12 (6), 1705-1718
• Global sensitivity analysis challenges in biological systems modeling A Kiparissides, SS Kucherenko, A Mantalaris, EN Pistikopoulos; Industrial & Engineering Chemistry Research 48 (15), 7168-7180

• Gkoutzioupa, Victoria (2024) Integrated experimental investigation of upstream and primary recovery operations to improve mammalian cell based process performance. Doctoral thesis, UCL (University College London).
• Booth, Matthew (2023) Development of a turbidostat photo-bioreactor to investigate the effects of process parameters on the physiology and growth of micro-algae. Doctoral thesis, UCL (University College London).
• Suarez Heredia, Ricardo (2023) On the in vitro and in silico investigation for the design and optimisation of nutrient supplementation strategies for improved and intensified mammalian cell cultures. Doctoral thesis, UCL (University College London).
• Sanchez Tarre, Victor (2021) A combined modelling and experimental characterisation of Chlamydomonas reinhardtii under monochromatic LED illumination. Doctoral thesis, UCL (University College London).
• Lularevic, Maximilian (2020) A combined mathematical and experimental investigation of lactate metabolism in industrial CHO cell cultures. Doctoral thesis, UCL (University College London)